靶向蛋白降解（TPD）是一项革命性技术，它能够利用包括泛素-蛋白酶体和溶酶体途径在内的天然细胞过程，选择性地消除特定的相关蛋白质。TPD 技术在治疗癌症、神经退行性疾病、自身免疫性疾病、炎症、病毒和细菌感染等各种疾病方面前景广阔。鉴于 TPD 有潜力克服小分子药物和生物制剂等传统药物模式所面临的挑战，它已赢得了全球学术界、制药业和投资者的极大关注。
Targeted protein degradation (TPD) stands as a revolutionary technology capable of selectively eliminating specific proteins of interest by leveraging natural cellular processes, including the ubiquitin-proteasome and lysosome pathways. TPD technology holds immense promise for the treatment of diverse diseases, ranging from cancer, neurodegenerative diseases, autoimmune disorders, inflammatory ailments, to viral and bacterial infections. Given its potential to overcome the challenges associated with traditional drug modalities like small molecules and biologics, TPD has garnered significant attention from academia, pharmaceutical industry, and investors world-wide.
本次研讨会的主题将围绕通过化学和生物创新开发和应用 TPD 技术展开，该技术不仅可以作为一种研究工具来探究和发现新的生物学特性，还可以作为一种治疗方法来治疗人类疾病。欢迎加入这场将在中国深圳举办的激动人心的研讨会，我们将与来自世界各地具有不同背景的同行们一起进行热烈的讨论和交流，并共同探索精彩的演讲和海报展示。
The theme of this symposium will be centered on development and application of TPD through chemical and biological innovations, serving not only as a research tool to interrogate and uncover new biology but also as a therapeutic modality to treat human diseases. Join us in lively discussion, networking opportunities with colleagues from diverse backgrounds worldwide, and to discover inspiring presentations and poster sessions at this exciting gathering in Shenzhen, China.
会议时间：
2024 年 11 月 12 日-14 日
Date: November 12-14, 2024
会议地点: 广东省深圳市光明区天安云谷国际会议中心
Venue: Cloud Park International Conference Center, Guangming District, Shenzhen, Guangdong, China
Deadline for Registration: November 9, 2024
Poster Size：Width 80 cm × Height 120 cm
Language: English (No simultaneous interpretation)
Proteolysis targeting chimera (PROTAC)
Molecular glue and induced proximity
Targeted protein degradation (TPD) in drug discovery and development
Membrane protein degradation (MPD)
Structural biology, proteomics, and new modalities
深圳医学科学院 Shenzhen Medical Academy of Research and Translation
深圳湾实验室 Shenzhen Bay Laboratory
斯坦福大学 Stanford University
邓迪大学 University of Dundee
深圳湾实验室 Shenzhen Bay Laboratory
1. 请于 2024 年 11 月 9 日前通过网站填写注册信息（长按二维码进入会议网站）。
1. Please fill in your registration information before November 9, 2024 via
the website:
https://symposia.smart.org.cn
2. 会议注册费：注册费包含 11 月 12 日至 14 日的午餐，以及 11 月 13 日的晚餐。
2. Registration Fee: The registration fee includes lunch on Nov. 12 through 14, and dinner on Nov. 13.
Please upload valid documents for review if you are a student.
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国际支付
International Payment
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1. 会议不设现场报名，请于 2024 年 11 月 9 日前完成报名与缴费。
1. The conference does not accept on-site registration. Please complete the registration and payment before November 9, 2024.
2. When making the transfer, please include the following note: TPD+your name.
3. 注册费电子发票将于会后 15 个工作日内发送至注册邮箱。
3. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the symposium.
4. 11 月 11 日 18:00 后取消参会将无法申请退款。
4. Refunds will not be available after 18:00 on November 11.
本次会议设有墙报展示环节，并设优秀墙报奖。我们诚邀您提交题目，参与墙报展示会（鼓励展示最新研究进展或未发表的研究课题）。
This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your topics and participate in the poster presentation (latest research advancements or unpublished research topics are encouraged).
How to participate: Upload poster information to the registration website.
墙报要求：
若您参与墙报展示，请自行打印并携带至会议现场，交由工作人员在指定位置张贴。
Poster requirements:
If you participate in the poster presentation, please print the poster yourself and bring it to the conference venue to be posted in the designated area by the staff.
Poster size:
Width 80 cm × Height 120 cm
墙报申请截止日期：
2024 年 11 月 9 日
Deadline:
November 9, 2024
本次会议不统一安排住宿，参会代表可自行联系附近酒店。
We do not provide centralized accommodation for this conference. Participants can arrange their own accommodation by contacting nearby hotels.
EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区新湖街道圳美社区圳园路 98 号（距离会场步行 200 米，步行 3 分钟）
Address: No.98 Zhenyuan Road, Zhenmei Community, Xinhu Street, Guangming District, Shenzhen. (The hotel is 200 metres from the conference venue, which takes 3 mins by foot.)
Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区圳美大道 68 号（距离会场步行 200 米，步行 3 分钟）
Address: No.68 Zhenmei Road, Guangming District, Shenzhen.(The hotel is 200 metres from the conference venue, which takes 3 mins by foot.)
Guangming CIMC Executive Apartments Hotel
地址：深圳市光明区凤凰街道侨明路中集行政公寓酒店（距离会场 7.6 公里，驾车 22 分钟）
Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen. (The hotel is 7.6 kilometers from the conference venue, which takes 22 mins by car.)
If you have any question, please contact:
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